个人简介

侯宗坤，副教授，贵州医科大学生物与工程学院青年教师。毕业于重庆大学生物工程学院生物医学工程专业，获博士学位。中国生物医学工程学会会员。主要研究领域是脑生物力学，擅长类器官病理模型的设计和应用。参与并主持多项国家及省级课题。目前已在国际期刊上发表十余篇论文，授权专利两项。

主要研究方向

(1)脑生物力学

(2)环境毒理学

近年来发表文章

[1]Li M, Sun H, Hou Z, et al. Engineering the physical microenvironment into neural organoids for neurogenesis and neurodevelopment[J]. Small, 2024, 20(6): 2306451.

[2]Meng R., Hao S* Sun C., Hou Z., Hou Y., Wang L., Deng P., Deng J., Yang Y., Xia H., Wang B.*, Qing R.*, Zhang S.* Reverse-QTY code design of active human serum albumin self-assembled amphilic nanoparticles for effective anti-tumor drug doxorubincin release in mice. Proceedings of the National Academy of Science, U.S.A. 2023, 120，e2220173120.

[3]Hou Z, Deng J, Cheng G, Hao S, Wang B. Distinct accumulation of nanoplastics in human intestinal organoids [J]. Science of the Total Environment, 2022, 838: 155811.

[4]Li M.; Hou Z.; Meng R..; Hao S *, Wang B.* Unraveling the potential human health risks from used disposable face mask-derived micro/nanoplastics during the COVID-19 pandemic scenario: a critical review. Environment Internation 2022, 170, 170644. .

[5]Hou Z, Li, X, Ren P, Gong Y, Guo T, Krafft P, Hao S, Wang B. Computational characterization of hemorheology in the lenticulostriate arteries predicts the location of vessel rupture during hypertensive intracerebral hemorrhage [J]. Brain Hemorrhages, 2022, 3(1): 5-13.

[6]Wang Y1, Hou Z1, Gong Y, Hao S, Wang B. Proteomic analysis of rat brain related to mass effect after experimental intracerebral hemorrhage [J]. Brain Hemorrhages, 2021, 2(3): 101-105.

[7]Hou Z, Zhu L, Meng R, Wang B. Hypolipidemic and antioxidant activities of Trichosanthes kirilowii maxim seed oil and flavonoids in mice fed with a high-fat diet [J]. Journal of Food Biochemistry, 2020, 44(8): e13272.

[8]Hou Z., Hao, S., Wang B. The mechanical mechanism of cortical folding on 3d cerebral organoids [J]. Molecular & Cellular Biomechanics, 2019(16), 145-145.

[9]Hou Z，Ji Q, Yang L，Gao Z，and Wang B．Extraction Optimization， Preliminary Characterization and Antioxidant Activity of Trichosanthes kirilowii Maxim Seed Oil [J]．Grasas Y Aceites．2017(3).

(1)国家自然科学基金委员会, 面上项目, 32371373,2024-01-01 至 2027-12-31, 50万元, 在研, 参与

(2)国家自然科学基金委员会, 地区科学基金项目, 12362029, 2024-01-01 至 2027-12-31, 32万元, 在研, 参与

(3)贵州省科学技术厅, 一般项目, 黔科合基础-ZK[2024]一般 175, 2024-04-01至2027-03-31, 10万元, 在研, 主持

(4)贵州省卫生健康委科学技术基金项目, 2024GZWJKJXM0217, 2024-1-1至2025-12-31,1万元，在研，主持

(5)国家自然科学基金委员会, 面上项目, 11972099, 2020-01-01 至 2023-12-31, 63万元, 资助期满, 参与