个人简介

贾义，男，博士，教授，博/硕士生导师。2013年毕业于华中科技大学。贵州省高层次创新型人才“千层次”人才，生物医学工程学科青年骨干教师，苏州大学访问学者；致力于硒的化学生物学功能研究，主要研究微量元素硒和硒蛋白的肿瘤免疫和神经免疫功能，及其在肿瘤和神经疾病治疗中的作用；近年来在国内外专业杂志发表论文40余篇；主持国家自然科学基金4项、贵州省科学技术基金3项，生物无机化学与药物湖北省重点实验室开放基金1项。

主要研究方向

(1)肿瘤免疫与神经免疫

(2)微量元素化学生物学

近年来发表文章

[1]Li M#,  Xie Y#, Zhang J#, Zhou X, Gao L,  He M,  Liu X,  Miao X,  Liu Y,  Cao R,  Jia Y*,  Zeng Z*,  Liu L*. Intratumoral injection of mRNA encoding Survivin in combination with STAT3 inhibitor stattic enhances antitumor effects. Cancer letters, 2024, 598: 217111.

[2]Liu Y#, Xia H#, Wang Y, Han S, Liu Y, Zhu S, Wu Y, Luo J, Dai J*, Jia Y*. Prognosis and immunotherapy in melanoma based on selenoprotein K-related signature. International Immunopharmacology, 2024, 137: 112436.

[3]Jia Y#,*, Zhang X#, Wang Y, Liu Y, Dai J, Zhang L, Wu X, Zhang J, Xiang H, Yang Y, Zeng Z, Chen Y. Knocking out selenium binding protein 1 induces depressive-like behavior in mice. Biological Trace Element Research, 2024, 202(7): 3149-3162.

[4]Xia H#, Wang Y#, Dai J, Zhang X, Zhou J*, Zeng Z*, Jia Y*. Selenoprotein K is essential for the migration and phagocytosis of immature dendritic cells. Antioxidants, 2022, 11(7):1264.

[5]Zhang X#, Zhang L#, Xia K#, Dai J, Huang J, Wang Y, Zhu G, Hu Z, Zeng Z*, Jia Y*. Effects of dietary selenium on immune function of spleen in mice. Journal of Functional Foods, 2022, 89:104914.

[6]Jia Y#,*, Zhang L#, Liu X. Zhang S, Dai J, Huang J, Chen J, Wang Y, Zhou J, Zeng Z*. Selenium can regulate the differentiation and immune function of human dendritic cells. Biometals, 2021, 34(6):1365-1379.

[7]Xia H#, Zhang L#, Dai J, Liu X, Zhang X, Zeng Z*, Jia Y*. Effect of selenium and peroxynitrite on immune function of immature dendritic cells in humans. Medical Science Monitor, 2021, 27:e929004.

[8]Zhang L#, Xia H#, Xia K, Liu X, Zhang X, Dai J, Zeng Z, Jia Y*. Selenium regulation of the immune function of dendritic cells in mice through the ERK, Akt and RhoA/ROCK pathways. Biological Trace Element Research, 2021, 199(9): 3360-3370.

[9]Jia Y*, Dai J, Zeng Z*. Potential relationship between the selenoproteome and cancer. Molecular and Clinical Oncology, 2020, 13(6): 83.

[10]Zhang L, Dai J, Zeng Z*, Jia Y*. Nitric oxide induces HepG2 cell death via extracellular signal-regulated protein kinase activation by regulating acid sphingomyelinase. Molecular Biology Reports, 2020, 47(10): 8353-8359.

[11]Jia Y*, Dai J, Zhang L, Xia H. Effect of exogenous zinc on MsrB1 expression and protein oxidation in human lens epithelial cells, Biological Trace Element Research, 2019, 190(1): 60-64.

[12]Jia Y*, Dai J, Zhang L, Xia H. Biological functions of selenium-binding protein 1 and its relationship with diseases. Progress in Biochemistry and Biophysics, 2019, 46(2): 128-137.

(1)国家自然科学基金地区项目，22167007，2025/01-2028/12，32万元，在研，主持

(2)国家自然科学基金地区项目，22167008，2022/01-2025/12，35万元，在研，主持

(3)生物无机化学与药物湖北省重点实验室开放基金项目，2020/01-2021/12，2万元，已结题，主持

(4)贵州省科学技术基金，黔科合基础[2019]1258号，2019/01-2021/12，10万元，已结题，主持

(5)国家自然科学基金地区项目，21867007，2019/01-2022/12，38万元，已结题，主持

(6)贵州省科技厅-贵州医科大学联合基金，黔科合LH字[2016]7372，2016/12-2019/12，6万元，已结题，主持

(7)国家自然科学基金地区项目，21561006，2016/01-2019/12，45.6万元，已结题，主持

(8)贵州省科学技术基金，黔科合J字[2014]2028号，2014/08-2017/08，4万元，已结题，主持

(9)贵阳医学院博士启动基金，院基金合同字第007号，2014/10-2016/09，2万元，已结题，主持